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SC-31155

Santa Cruz Biotechnology
Part Number SC-31155
Manufacturer Santa Cruz Biotechnology
Description EGFR (N-20)
Published Jul 16, 2009
Detailed Description SANTA CRUZ BIOTECHNOLOGY, INC. www.DataSheet4U.com EGFR (N-20): sc-31155 The Power to Question BACKGROUND The EGF rece...
Datasheet PDF File SC-31155 PDF File

SC-31155
SC-31155


Overview
SANTA CRUZ BIOTECHNOLOGY, INC.
www.
DataSheet4U.
com EGFR (N-20): sc-31155 The Power to Question BACKGROUND The EGF receptor family comprises several related receptor tyrosine kinases that are frequently overexpressed in a variety of carcinomas.
Members of this receptor family include EGFR (HER1), Neu (ErbB-2, HER2), ErbB-3 (HER3) and ErbB-4 (HER4), which form either homodimers or heterodimers upon ligand binding.
Exons in the EGFR gene product are frequently either deleted or duplicated to produce deletion mutants (DM) or tandem duplication mutants (TDM), respectively, which are detected at various molecular weights.
EGFR binds several ligands, including epidermal growth factor (EGF), trans...



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