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SC-8986

Part Number	SC-8986
Manufacturer	ETC
Description	HNF-1 (H-205)
Published	Apr 8, 2005
Detailed Description	Santa Cruz Biotechnology, Inc. SANTA CRUZ HNF-1 (H-205): sc-8986 BIOTECHNOLOGY BACKGROUND HNF-1 (α and β), HNF-3 (α, ...
Datasheet	SC-8986 PDF File

Overview

Santa Cruz Biotechnology, Inc.
SANTA CRUZ HNF-1 (H-205): sc-8986 BIOTECHNOLOGY BACKGROUND HNF-1 (α and β), HNF-3 (α, β and γ), HNF-4 (α and γ), and HNF-6 compose, in part, a homoeprotein family designated the Hepatocyte Nuclear Factor family (1-4).
The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney, small intestine and thymus (1).
HNF-3α, HNF-3β and HNF-3γ regulate the transcription of numerous hepatocyte genes in adult liver.
HNF-3α and HNF-3β have also been shown to be involved in gastrulation events such as body axis formation (2,4).
HNF-4 α and HNF-4 γ have been shown to be important for early embryo development.
HNF-4a i...

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